The NRI difference

Methodology built for your specific study

Two failure modes exist in nutraceutical research. Pharmaceutical CROs apply drug trial assumptions to botanicals. Budget CROs cut corners on measurement and compliance. NRI does neither.

What goes wrong elsewhere
App-based surveys with no validation
Proxy biomarkers that miss real effects
Populations that do not match your consumer
Drug-protocol blinding that fails for botanicals
High dropout, low data integrity
Studies that cannot substantiate claims
NRI standard
Proprietary validated psychometrics matched to your claims
Biomarkers plus validated self-report for complete measurement
Consumer-matched participant populations
Psychologically-driven blinding protocols
95%+ average participant retention
Published in peer-reviewed journals
On proprietary measurement

NRI has developed and validated psychometric scales specifically for natural product research in non-diseased populations: the NRI Stress Response Inventory, NRI Energy Scale, NRI Menopause Symptom Scale, NRI Sleep Scale, and NRI Cognition Scale. These instruments capture what consumers actually experience at the effect sizes that matter for nutraceuticals.

How we work

Methodology that holds up in peer review and in the market

Every NRI trial is PI-led from start to finish. The researcher who designs your trial is the researcher who runs it, analyzes it, and puts her name on the publication. No handoffs to junior staff.

01
Protocol design

Your compound, your claims, your consumer. Power analysis, endpoint selection, psychometric instrument selection or development, blinding strategy, intervention design.

02
IRB and regulatory

External IRB review, informed consent, clinical trial registration. All handled. NRI works with established IRB partners with zero FDA inspection findings.

03
Enrollment and execution

Participant recruitment from our established community of engaged volunteers. Active compliance monitoring throughout. 95%+ retention, near-perfect protocol compliance.

04
Analysis and publication

Statistical analysis in Stata v17. Downs and Black quality checklist. Manuscript preparation and peer-reviewed journal submission. Data that earns its place in the literature.

30+
Peer-reviewed publications
95%+
Average participant retention
25+
Years of nutraceutical trial expertise
The Botanical Lab at Stovehouse

Where the science becomes the experience

NRI's published research on botanicals, essential oils, and nutraceuticals powers everything at the Botanical Lab. The formulas you blend, the oils you smell, the classes you attend. All of it built on the same evidence base that produces peer-reviewed publications. Opening July 11 at Stovehouse in Huntsville, Alabama.

Aroma Blend Lab
from $18

Walk in. Choose a research-backed formula. Blend it yourself at the bench.

Explore →
Herbal Bar
from $22

Slow-infused botanical oils blended into a body oil, scrub, or salve.

Explore →
Olfactory Flights
from $28

A guided scent experience presented like a tasting menu.

Explore →
Classes and Workshops
from $55

Evidence-based, hands-on sessions several times a month.

See the schedule →
Grand Opening · Saturday July 11, 2026
Stovehouse · Suite 330 · Huntsville, Alabama · Free, walk in anytime
Explore the Lab

Jessie Cavanaugh, PhD

Twenty-five years building the methodological case for botanical medicine. Led the world's largest elderberry RCT, established lavender and tea tree safety in children across a three-paper epidemiological series, and developed proprietary psychometric instruments for nutraceutical outcomes. The researcher who designs your trial is the researcher who runs it, analyzes it, and puts her name on the publication.

Research you can read, not just claims you have to trust

Peer-reviewed publications across 25 years, with sponsors named in the record.

Complementary Therapies in Clinical Practice | Journal of Dietary Supplements |
Nutrition Research | Evidence-Based Complementary Medicine